The multidisciplinary field of pharmacometrics is an applied quantitative field that panders to the interpretation of pharmacological observations. It is a plausible bridge between observation collection and the understanding of medical science. In application, a pharmacometrics implementation involves mathematical and statistical models to aid in answering vital questions within this field. Mixed effects models became a primary analysis for population-based pharmacometric modeling (PK/PD) given the competence of this model to handle sparse data. In more depth, pharmacometrics contains pharmacostatistical modeling and simulation techniques that are considered for a wide variety of drug-response and relationship in pharmacotherapy.